LMI-070 (NVS-SM1)

Name: LMI-070 (NVS-SM1); MyBioSource
Brand: MyBioSource
SKU: MBS3602226
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602226

LMI070 (NVS-SM1, Branaplam ) is a potent SMN2 splice modulator (EC50=20 nM) that potential treatment of spinal muscular atrophy (SMA). More details

$240 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LMI-070, Biochemical

Full Product Name

LMI-070

Product Synonym Names

NVS-SM1; Branaplam

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

393.4821

Suitability

DMSO: 6.12mg/mL

Target

SMN2

Receptor

Others

Chemical Name

Phenol, 5-(1H-pyrazol-4-yl)-2-[6-[(2, 2, 6, 6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl]

SMILES

CC1(CC(CC(N1)(C)C)OC2=NN=C(C=C2)C3=C(C=C(C=C3)C4=CNN=C4)O)C

Molecular Formula

C22H27N5O2

CAS Number

1562338-42-4

Product Categories/Family for LMI-070 biochemical

Spinal Muscular Atrophy (SMA); Neurological Disease

Product References and Citations for LMI-070 biochemical

1. Calder AN, et al. J Med Chem. 2016 Nov 23; 59 (22):10067-10083.
2. Palacino J, et al. Nat Chem Biol. 2015 Jul; 11 (7):511-7.

Other Notes

Small volumes of LMI-070 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LMI-070 purchase

MBS3602226 is a biochemical targeting LMI-070.