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PTC-596

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602330

PTC-596 (PTC596) is a novel, orally active, small molecule inhibitor of BMI-1 that accelerates BMI-1 degradation, inhibits AML cells growth with IC50 of More details

$340 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTC-596, Biochemical
Full Product Name
PTC-596
Product Synonym Names
PTC 596; PTC596
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
420.347
Target
BMI-1
Receptor
BMI-1
Chemical Name
5-fluoro-2-(6-fluoro-2-methyl-1H-benzo[d]imidazol-1-yl)-N4-(4-(trifluoromethyl)phenyl)pyrimidine-4, 6-diamine
SMILES
NC1=C(F)C(NC2=CC=C(C(F)(F)F)C=C2)=NC(N3C4=CC(F)=CC=C4N=C3C)=N1
Molecular Formula
C19H13F5N6
CAS Number
1610964-64-1

Product Categories/Family for PTC-596 biochemical

Ovarian Cancer; Cancer

Structure of PTC-596 biochemical

PTC-596 Biochemical – Cat# MBS3602330

Product References and Citations for PTC-596 biochemical

1. Nishida Y, et al. Blood Cancer J. 2017 Feb 17; 7 (2):e527.
2, Eberle-Singh JA, et al. Clin Cancer Res. 2019 Jun 7. pii: clincanres.3281.2018. doi: 10.1158/1078-0432.CCR-18-3281.
3, Maeda A, et al. Oncotarget. 2018 Jun 19; 9 (47):28547-28560.

Other Notes

Small volumes of PTC-596 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTC-596 purchase

MBS3602330 is a biochemical targeting PTC-596.
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