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INCB053914

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602376

INCB053914 (INCB-053914) is a novel potent, and selective ATP-competitive, pan-PIM kinase inhibitor with IC50 of 0.24/30.0/0.12 nM for PIM1/2/3, respectively. More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INCB053914, Biochemical
Full Product Name
INCB053914
Product Synonym Names
INCB-053914
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
513.521
Target
Pim
Receptor
Pim
Chemical Name
N-((R)-4-((3R, 4R, 5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl)-7-hydroxy-6, 7-dihydro-5H-cyclopenta[b]pyridin-3-yl)-6-(2, 6-difluorophenyl)-5-fluoropicolinamide
SMILES
O=C(NC1=CN=C2C(CC[C@H]2O)=C1N3C[C@@H](N)[C@H](O)[C@@H](C)C3)C4=NC(C5=C(F)C=CC=C5F)=C(F)C=C4
Molecular Formula
C26H26F3N5O3
CAS Number
1620012-39-6

Product Categories/Family for INCB053914 biochemical

Solid Tumors; JAK/STAT Signaling; Cancer

Structure of INCB053914 biochemical

INCB053914 Biochemical – Cat# MBS3602376

Product References and Citations for INCB053914 biochemical

1. Koblish H, et al. PLoS One. 2018 Jun 21; 13 (6):e0199108.

Other Notes

Small volumes of INCB053914 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INCB053914 purchase

MBS3602376 is a biochemical targeting INCB053914.
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