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DLK-IN-14

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602382

A potent, selective, CNS penetrant dual leucine zipper kinase (DLK, MAP3K12) inhibitor with Ki of 3 nM. More details

$550 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DLK-IN-14, Biochemical
Full Product Name
DLK-IN-14
Product Synonym Names
DLK inhibitor 14; MAP3K12-IN-14
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
423.44
Suitability
DMSO: 62.5mg/mL (147.60mM)
Target
MEK
Receptor
MEK
Chemical Name
2-Pyridinamine, 5-[1-(1-methylethyl)-5-[(1alpha, 5alpha, 6alpha)-3-(3-oxetanyl)-3-azabicyclo[3.1.0]hex-6-yl]-1H-pyrazol-3-yl]-3-(trifluoromethoxy)
SMILES
CC(N1C([C@@H]2[C@]3([H])[C@@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C
Molecular Formula
C20H24F3N5O2
CAS Number
1620574-24-4

Product Categories/Family for DLK-IN-14 biochemical

MAPK/ERK Signaling

Structure of DLK-IN-14 biochemical

DLK-IN-14 Biochemical – Cat# MBS3602382

Product References and Citations for DLK-IN-14 biochemical

1. Patel S, et al. J Med Chem. 2017 Oct 12; 60 (19):8083-8102.

Other Notes

Small volumes of DLK-IN-14 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLK-IN-14 purchase

MBS3602382 is a biochemical targeting DLK-IN-14.
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