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MLi-2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602407

A potent, selective, orally available and brain-penetrant LRRK2 inhibitor with kinase IC50 of 0.76 nM, cellular IC50 of 1.4 nM (dephosphorylation of LRRK2 pSer935 LRRK2). More details

$255 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MLi-2, Biochemical
Full Product Name
MLi-2
Product Synonym Names
MLi2; Mli 2
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
379.4555
Suitability
DMSO: >=26mg/mL
Target
LRRK2
Receptor
LRRK2
Chemical Name
1H-Indazole, 3-[6-[(2R, 6S)-2, 6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-, rel
SMILES
CC1(OC2=CC3=C(NN=C3C4=CC(N5C[C@H](C)O[C@H](C)C5)=NC=N4)C=C2)CC1
Molecular Formula
C21H25N5O2
CAS Number
1627091-47-7

Product Categories/Family for MLi-2 biochemical

Autophagy; Neurological Disease

Structure of MLi-2 biochemical

Mli-2 Biochemical – Cat# MBS3602407

Product References and Citations for MLi-2 biochemical

1. Scott JD, et al. J Med Chem. 2017 Apr 13; 60 (7):2983-2992.
2. Fell MJ, et al. J Pharmacol Exp Ther. 2015 Dec; 355 (3):397-409.
3. Volpicelli-Daley LA, et al. J Neurosci. 2016 Jul 13; 36 (28):7415-27.

Other Notes

Small volumes of MLi-2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLi-2 purchase

MBS3602407 is a biochemical targeting MLi-2.
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