PFI-2 (R)-PFI-2)

Name: R)-PFI-2; MyBioSource
Brand: MyBioSource
SKU: MBS3602414
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602414

A first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM. More details

$240 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PFI-2, Biochemical

Full Product Name

PFI-2

Product Synonym Names

R)-PFI-2

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

499.5215

Suitability

10mM in DMSO

Target

HMTase

Receptor

SETD7

Chemical Name

6-Isoquinolinesulfonamide, 8-fluoro-1, 2, 3, 4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]

SMILES

C1CCN(C1)C(=O)[C@@H](CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC(=C4CNCCC4=C3)F

Molecular Formula

C23H25F4N3O3S

CAS Number

1627676-59-8

Product Categories/Family for PFI-2 biochemical

Chromatin/Epigenetic; Other Indications

Product References and Citations for PFI-2 biochemical

1. Barsyte-Lovejoy D, et al. Proc Natl Acad Sci U S A. 2014 Sep 2; 111 (35):12853-8.
2. Niu Y, et al. Sci Rep. 2017 Apr 18; 7:46547.

Other Notes

Small volumes of PFI-2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PFI-2 purchase

MBS3602414 is a biochemical targeting PFI-2.