G1T38 (Lerociclib)

Name: G1T38 (Lerociclib); MyBioSource
Brand: MyBioSource
SKU: MBS3602425
Price: 255 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602425

G1T38 (Lerociclib, G1T 38) is a novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively. More details

$255 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

G1T38, Biochemical

Full Product Name

G1T38

Product Synonym Names

Lerociclib; G1T 38

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

474.613

Target

CDK

Receptor

CDK

Chemical Name

2'-((5-(4-isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7', 8'-dihydro-6'H-spiro[cyclohexane-1, 9'-pyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyrimidin]-6'-one

SMILES

CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6

Molecular Formula

C26H34N8O

CAS Number

1628256-23-4

Product Categories/Family for G1T38 biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for G1T38 biochemical

1. Bisi JE, et al. Oncotarget. 2017 Jun 27; 8 (26):42343-42358.
2. Stice JP, et al. Mol Cancer Res. 2017 Jun; 15 (6):660-669.

Other Notes

Small volumes of G1T38 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G1T38 purchase

MBS3602425 is a biochemical targeting G1T38.