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Mavacamten (SAR-439152)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602489

Mavacamten (SAR-439152, MYK-461) is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mavacamten, Biochemical
Full Product Name
Mavacamten
Product Synonym Names
SAR-439152; MYK-461
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
273.336
Suitability
10mM in DMSO
Target
Myosin
Receptor
Myosin
Chemical Name
(S)-3-isopropyl-6-((1-phenylethyl)amino)pyrimidine-2, 4(1H, 3H)-dione
SMILES
O=C1N(C(C)C)C(C=C(N[C@H](C2=CC=CC=C2)C)N1)=O
Molecular Formula
C15H19N3O2
CAS Number
1642288-47-8

Product References and Citations for Mavacamten biochemical

1. Green EM, et al. Science. 2016 Feb 5; 351 (6273):617-21.
2. Stern JA, et al. PLoS One. 2016 Dec 14; 11 (12):e0168407.
3. Kawas RF, et al. J Biol Chem. 2017 Oct 6; 292 (40):16571-16577.

Other Notes

Small volumes of Mavacamten biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mavacamten purchase

MBS3602489 is a biochemical targeting Mavacamten.
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