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CCT251545

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602536

CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT… More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCT251545, Biochemical
Full Product Name
CCT251545
Product Synonym Names
CCT 251545; CCT-251545
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
421.9225
Suitability
DMSO: >=50mg/mL
Target
CDK
Receptor
CDK
Chemical Name
2, 8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]
SMILES
O=C1NCCC12CCN(C3=C(Cl)C=NC=C3C4=CC=C(C5=CN(C)N=C5)C=C4)CC2
Molecular Formula
C23H24ClN5O
CAS Number
1661839-45-7

Product Categories/Family for CCT251545 biochemical

Angiogenesis; Cancer

Structure of CCT251545 biochemical

CCT251545 Biochemical – Cat# MBS3602536

Product References and Citations for CCT251545 biochemical

1. Mallinger A, et al. J Med Chem. 2015 Feb 26; 58 (4):1717-35.
2. Dale T, et al. Nat Chem Biol. 2015 Dec; 11 (12):973-980.

Other Notes

Small volumes of CCT251545 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCT251545 purchase

MBS3602536 is a biochemical targeting CCT251545.
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