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IPI-549

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602582

IPI-549 (IPI549) is a potent, highly selective, orally active inhibitor of PI3Kgamma with IC50 of 16 nM. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IPI-549, Biochemical
Full Product Name
IPI-549
Product Synonym Names
IPI549; IPI 549
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
528.564
Suitability
DMSO: 15mg/mL
Target
PI3K
Receptor
PI3K
Chemical Name
Pyrazolo[1, 5-a]pyrimidine-3-carboxamide, 2-amino-N-[(1S)-1-[1, 2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]
SMILES
O=C1N(C2=CC=CC=C2)C([C@@H](NC(C3=C(N=CC=C4)N4N=C3N)=O)C)=CC5=CC=CC(C#CC6=CN(C)N=C6)=C51
Molecular Formula
C30H24N8O2
CAS Number
1693758-51-8

Product Categories/Family for IPI-549 biochemical

Solid Tumors; PI3K/Akt/mTOR signaling; Cancer

Product References and Citations for IPI-549 biochemical

1. Evans CA, et al. ACS Med Chem Lett. 2016 Jul 22; 7 (9):862-7.
2. De Henau O, et al. Nature. 2016 Nov 17; 539 (7629):443-447.

Other Notes

Small volumes of IPI-549 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IPI-549 purchase

MBS3602582 is a biochemical targeting IPI-549.
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