FGF-401 (NVP-FGF401)

Name: FGF-401 (NVP-FGF401); MyBioSource
Brand: MyBioSource
SKU: MBS3602608
Price: 270 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602608

FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM. More details

$270 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FGF-401, Biochemical

Full Product Name

FGF-401

Product Synonym Names

NVP-FGF401; Roblitinib; FGF401

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

506.567

Suitability

DMSO: 6mg/mL (Need Ultrasonic)

Target

FGFR

Receptor

FGFR4

Chemical Name

1, 8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3, 4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]

SMILES

CN1CC(N(CC2=CC(CCCN3C(NC4=CC(NCCOC)=C(C#N)C=N4)=O)=C3N=C2C=O)CC1)=O

Molecular Formula

C25H30N8O4

CAS Number

1708971-55-4

Product Categories/Family for FGF-401 biochemical

Liver Cancer; Angiogenesis; Cancer

Product References and Citations for FGF-401 biochemical

1. Diana Graus Porta, et al. Abstract 2098: NVP-FGF401, a first-in-class highly selective and potent FGFR4 inhibitor for the treatment of HCC, AACR.
2. Patent WO2015059668A1, compound example 83.

Other Notes

Small volumes of FGF-401 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF-401 purchase

MBS3602608 is a biochemical targeting FGF-401.