Nepicastat (SYN117)

Name: Nepicastat (SYN117); MyBioSource
Brand: MyBioSource
SKU: MBS3602642
Price: 1170 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602642

Nepicastat (RS-25560-197, SYN-117) is a potent, selective, orally active inhibitor of dopamine-beta-hydroxylase (DBH) with IC50 of 8.5 and 9.0 nM for bovine and human DBH, respectively. More details

$1170 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nepicastat, Biochemical

Full Product Name

Nepicastat

Product Synonym Names

SYN117; RS-25560-197; SYN-117; SYN 117

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

295.35

Suitability

DMSO: >=48mg/mL

Target

Dopamine beta-hydroxylase

Receptor

Dopamine beta-hydroxylase

Chemical Name

2H-Imidazole-2-thione, 5-(aminomethyl)-1-[(2S)-5, 7-difluoro-1, 2, 3, 4-tetrahydro-2-naphthalenyl]-1, 3-dihydro

SMILES

C1CC2=C(CC1N3C(=CNC3=S)CN)C=C(C=C2F)F

Molecular Formula

C14H15F2N3S

CAS Number

173997-05-2

Product Categories/Family for Nepicastat biochemical

Hypertension; Metabolic Enzyme/Protease; Cardiovascular Disease

Product References and Citations for Nepicastat biochemical

1. Stanley WC, et al. Br J Pharmacol. 1997 Aug; 121 (8):1803-9.
2. Stanley WC, et al. J Cardiovasc Pharmacol. 1998 Jun; 31 (6):963-70.
3. Sabbah HN, et al. Circulation. 2000 Oct 17; 102 (16):1990-5.
4. Schroeder JP, et al. Neuropsychopharmacology. 2010 Nov; 35 (12):2440-9.

Other Notes

Small volumes of Nepicastat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nepicastat purchase

MBS3602642 is a biochemical targeting Nepicastat.