• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MZ1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602715

MZ1 is a PROTAC that tethers JQ1 to a ligand for the E3 ubiquitin ligase VHL, triggers, induces degradation of the BET bromodomain BRD4. More details

$310 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MZ1, Biochemical
Full Product Name
MZ1
Product Synonym Names
MZ-1; MZ 1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1002.644
Suitability
DMSO: 25mg/mL (24.93mM)
H2O: <0.1mg/mL
Target
PROTAC
Receptor
PROTAC
Chemical Name
(2S, 4R)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2, 3, 9-trimethyl-6H-thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepin-6-yl)-4, 16-dioxo-6, 9, 12-trioxa-3, 15-diazaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
SMILES
O=C([C@H]1N(C([C@@H](NC(COCCOCCOCCNC(C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2)=O)=O)C(C)(C)C)=O)CCC1)NCC6=CC=C(C7=C(C)N=CS7)C=C6
Molecular Formula
C49H60ClN9O8S2
CAS Number
1797406-69-9

Product Categories/Family for MZ1 biochemical

PROTACs

Structure of MZ1 biochemical

MZ1 Biochemical – Cat# MBS3602715

Product References and Citations for MZ1 biochemical

1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21; 10 (8):1770-7.

Other Notes

Small volumes of MZ1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MZ1 purchase

MBS3602715 is a biochemical targeting MZ1.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000