TPX 0005 (Ropotrectinib)

Name: TPX 0005 (Ropotrectinib); MyBioSource
Brand: MyBioSource
SKU: MBS3602751
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602751

TPX 0005 (Ropotrectinib, Repotrectinib, TPX0005) is a novel ALK/ROS1/TRK inhibitor. More details

$260 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TPX 0005, Biochemical

Full Product Name

TPX 0005

Product Synonym Names

Ropotrectinib; Repotrectinib; TPX0005

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

355.373

Suitability

DMSO: >=83.3mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)

Target

ALK

Receptor

ALK; Src

Chemical Name

(7S, 13R)-11-fluoro-6, 7, 13, 14-tetrahydro-7, 13-dimethyl-1, 15-etheno-1H-pyrazolo[4, 3-f][1, 4, 8, 10]benzoxatriazacyclotridecin-4(5H)-one

SMILES

O=C1NC[C@H](C)OC2=CC=C(F)C=C2[C@@H](C)NC3=NC4=C1C=NN4C=C3

Molecular Formula

C18H18FN5O2

CAS Number

1802220-02-5

Product Categories/Family for TPX 0005 biochemical

Solid Tumors; Angiogenesis; Cancer

Product References and Citations for TPX 0005 biochemical

1. Zhai D, et al. DOI: 10.1158/1538-7445.AM2016-2132 Published July 2016
2. J.J. Cui, et al. DOI: http://dx.doi.org/10.1016/S0959-8049 (16)32675-2.
3.Drilon A, et al. Cancer Discov. 2018 Aug 9. pii: CD-18-0484.

Other Notes

Small volumes of TPX 0005 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TPX 0005 purchase

MBS3602751 is a biochemical targeting TPX 0005.