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BAY-1436032

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602757

BAY-1436032 (BAY1436032) is a potent, selective, orally available inhibitor of pan-mutant IDH1 with IC50 of 15 nM for both IDH1 R132H and R132C, respectively. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BAY-1436032, Biochemical
Full Product Name
BAY-1436032
Product Synonym Names
BAY1436032; BAY 1436032
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
489.54
Suitability
DMSO: 125mg/mL (255.35mM)
H2O: <0.1mg/mL
Target
IDH
Receptor
IDH
Chemical Name
3-(2-((4-(trifluoromethoxy)phenyl)amino)-1-((1R, 5R)-3, 3, 5-trimethylcyclohexyl)-1H-benzo[d]imidazol-5-yl)propanoic acid
SMILES
O=C(O)CCC1=CC=C2N([C@H]3CC(C)(C)C[C@@H](C)C3)C(NC4=CC=C(OC(F)(F)F)C=C4)=NC2=C1
Molecular Formula
C26H30F3N3O3
CAS Number
1803274-65-8

Product Categories/Family for BAY-1436032 biochemical

Blood cancer; Metabolic Enzyme/Protease; Cancer

Structure of BAY-1436032 biochemical

BAY-1436032 Biochemical – Cat# MBS3602757

Product References and Citations for BAY-1436032 biochemical

1. Pusch S, et al. Acta Neuropathol. 2017 Apr; 133 (4):629-644.
2. Chaturvedi A, et al. Leukemia. 2017 Oct; 31 (10):2020-2028.
3. Gokul S, et al. CNS Neurol Disord Drug Targets. 2017; 16 (6):636-637.

Other Notes

Small volumes of BAY-1436032 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY-1436032 purchase

MBS3602757 is a biochemical targeting BAY-1436032.
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