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GS-5734

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602773

GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays. More details

$425 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GS-5734, Biochemical
Full Product Name
GS-5734
Product Synonym Names
GS 5734; GS5734; Remdesivir
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
601.597
Suitability
DMSO: >=125mg/mL (207.44mM)
Target
Filovirus
Receptor
Filovirus
Chemical Name
2-ethylbutyl((S)-(((2R, 3S, 4R, 5R)-5-(4-aminopyrrolo[1, 2-b]pyridazin-7-yl)-5-cyano-3, 4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
SMILES
CCC(CC)COC([C@H](C)N[P@](OC[C@H]1O[C@](C2=CC=C3N2N=CC=C3N)(C#N)[C@H](O)[C@@H]1O)(OC4=CC=CC=C4)=O)=O
Molecular Formula
C28H36N5O8P
CAS Number
1809249-37-3

Product Categories/Family for GS-5734 biochemical

Ebola Virus Infection; Microbiology/Virology; Infection

Structure of GS-5734 biochemical

Gs-5734 Biochemical – Cat# MBS3602773

Product References and Citations for GS-5734 biochemical

1. Warren TK, et al. Nature. 2016 Mar 17; 531 (7594):381-5.
2. Jacobs M, et al. Lancet. 2016 Jul 30; 388 (10043):498-503.
3. Siegel D, et al. J Med Chem. 2017 Mar 9; 60 (5):1648-1661.

Other Notes

Small volumes of GS-5734 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GS-5734 purchase

MBS3602773 is a biochemical targeting GS-5734.
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