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LEM-14

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602786

LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM. More details

$270 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LEM-14, Biochemical
Full Product Name
LEM-14
Product Synonym Names
LEM14; LEM 14; LEM-14
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
478.567
Target
HMTase
Receptor
HMTase
Chemical Name
(R)-2-((4-(1-oxoisochromane-3-carbonyl)piperazin-1-yl)methyl)-5, 6, 7, 8-tetrahydrobenzo[4, 5]thieno[2, 3-d]pyrimidin-4(3H)-one
SMILES
O=C1C(C2=C(CCCC2)S3)=C3N=C(CN4CCN(C([C@@H](CC5=C6C=CC=C5)OC6=O)=O)CC4)N1
Molecular Formula
C25H26N4O4S
CAS Number
1814881-70-3

Product Categories/Family for LEM-14 biochemical

Chromatin/Epigenetic

Structure of LEM-14 biochemical

LEM-14 Biochemical – Cat# MBS3602786

Product References and Citations for LEM-14 biochemical

1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X (18)32443-4.

Other Notes

Small volumes of LEM-14 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LEM-14 purchase

MBS3602786 is a biochemical targeting LEM-14.
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