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BI-0252

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602794

A potent, highly selective, orally active MDM2-p53 interaction inhibitor with IC50 of 4 nM. More details

$1025 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BI-0252, Biochemical
Full Product Name
BI-0252
Product Synonym Names
BI 0252; BI0252
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
566.45
Target
MDM2-p53
Receptor
MDM2-p53
Chemical Name
4-[(3S, 3'S, 3'aS, 5'R, 6'aS)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1, 2, 3', 3'a, 4', 5', 6', 6'a-octahydro-1'H-spiro[indole-3, 2'-pyrrolo[3, 2-b]pyrrole]-5'-yl]benzoic acid
SMILES
ClC1=CC(NC([C@]23[C@@H](C4=CC=CC(Cl)=C4F)[C@H](C[C@@H](C5=CC=C(C(O)=O)C=C5)C6)[C@H]6N3CC7CC7)=O)=C2C=C1
Molecular Formula
C30H26Cl2FN3O3
CAS Number
1818291-27-8

Product Categories/Family for BI-0252 biochemical

Apoptosis; Other Indications

Structure of BI-0252 biochemical

Bi-0252 Biochemical – Cat# MBS3602794

Product References and Citations for BI-0252 biochemical

1. Gollner A, et al. J Med Chem. 2016 Nov 23; 59 (22):10147-10162.

Other Notes

Small volumes of BI-0252 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BI-0252 purchase

MBS3602794 is a biochemical targeting BI-0252.
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