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iJak-381

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602820

iJak-381 (iJak381) is a potent, selective inhalable and lung-restricted inhibitor of JAK1 with IC50 of 8.52 nM. More details

$340 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
iJak-381, Biochemical
Full Product Name
iJak-381
Product Synonym Names
iJak381
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
612.039
Target
JAK
Receptor
JAK
Chemical Name
N-(3-(5-chloro-2-(difluoromethoxy)phenyl)-1-(2-(4-((2-cyanoethyl)(methyl)amino)piperidin-1-yl)-2-oxoethyl)-1H-pyrazol-4-yl)pyrazolo[1, 5-a]pyrimidine-3-carboxamide
SMILES
O=C(C1=C2N=CC=CN2N=C1)NC3=CN(CC(N4CCC(N(CCC#N)C)CC4)=O)N=C3C5=CC(Cl)=CC=C5OC(F)F
Molecular Formula
C28H28ClF2N9O3
CAS Number
1831144-46-7

Product Categories/Family for iJak-381 biochemical

Structure of iJak-381 biochemical

Ijak-381 Biochemical – Cat# MBS3602820

Product References and Citations for iJak-381 biochemical

1. Dengler HS, et al. Sci Transl Med. 2018 Nov 21; 10 (468). pii: eaao2151. doi: 10.1126/scitranslmed.aao2151.

Other Notes

Small volumes of iJak-381 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for iJak-381 purchase

MBS3602820 is a biochemical targeting iJak-381.
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