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Mithramycin A (Plicamycin)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602838

A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. More details

$495 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mithramycin A, Biochemical
Full Product Name
Mithramycin A
Product Synonym Names
Plicamycin; PA 144; NSC 24559
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1085
Target
DNA/RNA Synthesis
Receptor
DNA/RNA Synthesis
Chemical Name
(2S, 3S)-3-((1S, 3S, 4R)-3, 4-dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S, 4R, 5R, 6R)-4-(((2S, 4R, 5S, 6R)-4-(((2S, 4S, 5R, 6R)-4, 5-dihydroxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran
SMILES
O=C1[C@@H](O[C@H]2C[C@@H](O[C@H]3C[C@@H](O[C@H]4C[C@](C)(O)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)[C@H](O)[C@@H](C)O2)[C@H]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)CC5=C1C(O)=C6C(O)=C(C)C(O[C@H]7C[C@@H](O[C@H]8C[C@@H](O)[C@H](O)[C@@H](C)O8)[C@H](O)[C@@H](C)O7)=CC6=C5
Molecular Formula
C52H76O24
CAS Number
18378-89-7

Product References and Citations for Mithramycin A biochemical

1. Boro A, et al. Int J Cancer. 2012 Nov 1; 131 (9):2153-64.
2. Lee TJ, et al. Mol Cancer Ther. 2006 Nov; 5 (11):2737-46.
3. Majee S, et al. Biochem Pharmacol. 1999 May 1; 57 (9):981-7.

Other Notes

Small volumes of Mithramycin A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mithramycin A purchase

MBS3602838 is a biochemical targeting Mithramycin A.
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