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MSI-1436 (Trodusquemine)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602875

An non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B1-405; antagonizes HER2 signaling. More details

$6100 / 5 mg +7 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MSI-1436, Biochemical
Full Product Name
MSI-1436
Product Synonym Names
Trodusquemine; Aminosterol-1436; MSI1436
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
685.0564
Suitability
10mM in DMSO
Target
Protein Phosphatase/PTP
Receptor
Protein Phosphatase/PTP
Chemical Name
Cholestane-7, 24-diol, 3-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-, 24-(hydrogen sulfate), (3beta, 5alpha, 7alpha, 24R)
SMILES
CC(C)C(CCC(C)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)NCCCNCCCCNCCCN)C)O)C)OS(=O)(=O)O
Molecular Formula
C37H72N4O5S
CAS Number
186139-09-3

Structure of MSI-1436 biochemical

MSI-1436 Trodusquemine Biochemical – Cat# MBS3602875

Product References and Citations for MSI-1436 biochemical

1. Krishnan N, et al. Nat Chem Biol. 2014 Jul; 10 (7):558-66.
2. Qin Z, et al. Biochem Biophys Res Commun. 2015 Feb 27; 458 (1):21-7.

Other Notes

Small volumes of MSI-1436 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSI-1436 purchase

MBS3602875 is a biochemical targeting MSI-1436.
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