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AMG-176

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602935

AMG-176 (AMG176) is a novel, potent and selective Mcl-1 inhibitor that binds with high affinity and selectivity to the BH3-binding groove of Mcl-1. More details

$1395 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AMG-176, Biochemical
Full Product Name
AMG-176
Product Synonym Names
AMG 176; AMG176
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
613.21
Suitability
DMSO: 62.5mg/mL (101.92mM)
Target
Bcl-2
Receptor
Bcl-2
Chemical Name
Spiro[5, 7-etheno-1H, 11H-cyclobut[i][1, 4]oxazepino[3, 4-f][1, 2, 7]thiadiazacyclohexadecine-2(3H), 1'(2'H)-naphthalen]-8(9H)-one, 6'-chloro-3', 4', 12, 13, 16, 16a, 17, 18, 18a, 19-decahydro-16-methoxy-11, 12-dimethyl-, 10, 10-dioxide, (1'S, 11R, 12S, 14E, 16S, 16aR, 18aR)
SMILES
O=C(N1)C2=CC(N(C[C@H]3[C@@H](CC3)[C@@H](OC)/C=C/C[C@H](C)[C@@H](C)S1(=O)=O)C4)=C(C=C2)OC[C@@]54CCCC6=CC(Cl)=CC=C65
Molecular Formula
C33H41ClN2O5S
CAS Number
1883727-34-1

Product Categories/Family for AMG-176 biochemical

Angiogenesis; Cancer

Structure of AMG-176 biochemical

AMG-176 Biochemical – Cat# MBS3602935

Product References and Citations for AMG-176 biochemical

1. Sean R. Caenepeel, et al. AACR Annual Meeting 2017; April 1-5, 2017.

Other Notes

Small volumes of AMG-176 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMG-176 purchase

MBS3602935 is a biochemical targeting AMG-176.
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