Lapaquistat (TAK475)

Name: Lapaquistat (TAK475); MyBioSource
Brand: MyBioSource
SKU: MBS3602962
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602962

A novel potent, competitive, orally active squalene synthase inhibitor with IC50 of 78 nM. More details

$425 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lapaquistat, Biochemical

Full Product Name

Lapaquistat

Product Synonym Names

TAK475; TAK 475; Lapaquistat acetate

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

645.146

Target

Other Targets

Receptor

Other Targets

Chemical Name

1-{2-[(3R, 5S)-1-(3-acetoxy-2, 2-dimethylpropyl)-7-chloro-1, 2, 3, 5-tetrahydro-2-oxo-5-(2, 3-dimethoxyphenyl)-4, 1-benzoxazepine-3-yl] acetyl} piperidin-4-acetic acid

SMILES

O=C(O)CC1CCN(C(C[C@H]2O[C@H](C3=CC=CC(OC)=C3OC)C4=CC(Cl)=CC=C4N(CC(C)(C)COC(C)=O)C2=O)=O)CC1

Molecular Formula

C33H41ClN2O9

CAS Number

189060-13-7

Product Categories/Family for Lapaquistat biochemical

Dyslipidemia; Cardiovascular Disease

Product References and Citations for Lapaquistat biochemical

1. Miki T, et al. J Med Chem. 2002 Sep 26; 45 (20):4571-80.
2. Amano Y, et al. Eur J Pharmacol. 2003 Apr 11; 466 (1-2):155-61.
3. Nishimoto T, et al. Br J Pharmacol. 2003 Jul; 139 (5):911-8.
4. Burnett JR. Curr Opin Investig Drugs. 2006 Sep; 7 (9):850-6.

Other Notes

Small volumes of Lapaquistat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lapaquistat purchase

MBS3602962 is a biochemical targeting Lapaquistat.