Pf-06815345 (PF 6815345)

Name: Pf-06815345 (PF 6815345); MyBioSource
Brand: MyBioSource
SKU: MBS3602982
Price: 1460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602982

PF-06815345 (PF 6815345) is a potent prodrug PCSK9 modulator that inhibits PCSK9 secretion in vitro translation assay. More details

$1460 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PF-06815345, Biochemical

Full Product Name

PF-06815345

Product Synonym Names

PF 6815345

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

598.036

Target

PCSK9

Receptor

PCSK9

Chemical Name

(S)-1-(5-(4-(4-((3-chloropyridin-2-yl)((R)-piperidin-3-yl)carbamoyl)-2-fluorophenyl)-1-methyl-1H-pyrazol-5-yl)-1H-tetrazol-1-yl)ethyl ethyl carbonate

SMILES

O=C(O[C@H](N1N=NN=C1C2=C(C3=CC=C(C(N(C4=NC=CC=C4Cl)[C@H]5CNCCC5)=O)C=C3F)C=NN2C)C)OCC

Molecular Formula

C27H29ClFN9O4

CAS Number

1900686-46-5

Product Categories/Family for PF-06815345 biochemical

Hypercholesterolemia; Cardiovascular Disease

Product References and Citations for PF-06815345 biochemical

1. McClure KF, et al. Angew Chem Int Ed Engl. 2017 Dec 18; 56 (51):16218-16222.
2. Daniel Pettersen, et al. Small molecule modulators of PCSK9-a literature and patent overview. Bioorg Med Chem Lett. 2018 Feb 26. pii: S0960-894X (18)30151-3.

Other Notes

Small volumes of PF-06815345 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-06815345 purchase

MBS3602982 is a biochemical targeting PF-06815345.