GLPG-2222 (ABBV-2222)

Name: GLPG-2222 (ABBV-2222); MyBioSource
Brand: MyBioSource
SKU: MBS3603006
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603006

GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM; is highly potent (5 nM) and efficacious in cells from multiple CF patient donors that have F508del homozygous mutation. More details

$530 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GLPG-2222, Biochemical

Full Product Name

GLPG-2222

Product Synonym Names

ABBV-2222; ABBV2222; GLPG2222

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

559.47

Target

CFTR

Receptor

CFTR

Chemical Name

4-[(2R, 4R)-4-({[1-(2, 2-difluoro-1, 3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3, 4-dihydro-2H-chromen-2-yl]benzoic acid

SMILES

FC(F)OC1=CC=C2C(O[C@@H](C3=CC=C(C(O)=O)C=C3)C[C@H]2NC(C4(C5=CC(OC(F)(F)O6)=C6C=C5)CC4)=O)=C1

Molecular Formula

C28H21F4NO7

CAS Number

1918143-53-9

Product Categories/Family for GLPG-2222 biochemical

Fibrosis; Apoptosis; Other Indications

Product References and Citations for GLPG-2222 biochemical

1. Wang X, et al. J Med Chem. 2017 Dec 18. doi: 10.1021/acs.jmedchem.7b01339.

Other Notes

Small volumes of GLPG-2222 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLPG-2222 purchase

MBS3603006 is a biochemical targeting GLPG-2222.