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dBET6

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603051

dBET6 is a highly cell-permeable, optimized chemical degrader of BET bromodomain BED4, does not directly affect CDK9 localization. More details

$265 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
dBET6, Biochemical
Full Product Name
dBET6
Product Synonym Names
dBET 6
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
841.381
Suitability
DMSO: 10mM (<1mg/mL refers to the product slightly soluble or insoluble)
Target
PROTAC
Receptor
BET
Chemical Name
6H-Thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[8-[[2-[[2-(2, 6-dioxo-3-piperidinyl)-2, 3-dihydro-1, 3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2, 3, 9-trimethyl-, (6S)
SMILES
O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Molecular Formula
C42H45ClN8O7S
CAS Number
1950634-92-0

Product Categories/Family for dBET6 biochemical

PROTACs

Structure of dBET6 biochemical

Dbet6 Biochemical – Cat# MBS3603051

Product References and Citations for dBET6 biochemical

1. Winter GE, et al. Mol Cell. 2017 Jul 6; 67 (1):5-18.e19.
2. Cancer Discov. 2017 Aug; 7 (8):794.

Other Notes

Small volumes of dBET6 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for dBET6 purchase

MBS3603051 is a biochemical targeting dBET6.
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