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PF-06855800

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603110

PF-06855800 (PF06855800) is a potent, selective, SAM competitive, BBB-penetrant, orally active inhibitor of protein arginine methyltransferase PRMT5 with Ki of 0.02 nM. More details

$955 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-06855800, Biochemical
Full Product Name
PF-06855800
Product Synonym Names
PF06855800
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
392.811
Target
HMTase
Receptor
HMTase
Chemical Name
(2R, 3S, 4R, 5R)-2-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)-5-(4-methyl-1H-pyrrolo[3, 2-c]pyridin-1-yl)tetrahydrofuran-3, 4-diol
SMILES
NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H]([C@@H](C4=CC=C(Cl)C(F)=C4)O)O3)O)O)C=C2)=NC=N1
Molecular Formula
C19H18ClFN2O4
CAS Number
1989620-04-3

Product Categories/Family for PF-06855800 biochemical

Chromatin/Epigenetic

Structure of PF-06855800 biochemical

Pf-06855800 Biochemical – Cat# MBS3603110

Product References and Citations for PF-06855800 biochemical

1. Indrawan J. Mcalpine, et al. Abstract 4857: Discovery of PF-06855800, a SAM competitive PRMT5 inhibitor with potent antitumor activity. DOI: 10.1158/1538-7445.AM2018-4857. AACR 2018.

Other Notes

Small volumes of PF-06855800 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-06855800 purchase

MBS3603110 is a biochemical targeting PF-06855800.
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