• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GDC-0077

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603203

GDC-0077 (RG-6114) is a potent, highly isoform selective inhibitor of PI3Kalpha, with IC50 of 0.038 nM. More details

$355 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDC-0077, Biochemical
Full Product Name
GDC-0077
Product Synonym Names
GDC0077; RG-6114; RG6114
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
407.378
Suitability
DMSO: >=180mg/mL (441.86mM)
Target
PI3K
Receptor
PI3K
Chemical Name
(S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5, 6-dihydrobenzo[f]imidazo[1, 2-d][1, 4]oxazepin-9-yl)amino)propanamide
SMILES
C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1
Molecular Formula
C18H19F2N5O4
CAS Number
2060571-02-8

Product Categories/Family for GDC-0077 biochemical

Breast Cancer; PI3K/Akt/mTOR signaling; Cancer

Structure of GDC-0077 biochemical

GDC-0077 Biochemical – Cat# MBS3603203

Product References and Citations for GDC-0077 biochemical

1. Kyle Edgar, et al. Abstract 156: Preclinical characterization of GDC-0077, a specific PI3K alpha inhibitor in early clinical development. AACR July 2017.

Other Notes

Small volumes of GDC-0077 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0077 purchase

MBS3603203 is a biochemical targeting GDC-0077.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000