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AZD 4205

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603274

AZD 4205 (AZD4205) is a potent, selective JAK1 inhibitor IC50 of 73 nM and Ki of 2.8 nM, shows high selectivity against JAK2 and JAK3 with IC50 of 13,233 nM and >30,000 nM respectively. More details

$265 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD 4205, Biochemical
Full Product Name
AZD 4205
Product Synonym Names
AZD4205
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
521.601
Target
JAK
Receptor
JAK
Chemical Name
(R)-N-(3-(2-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide
SMILES
CC(C(=O)NC1=CC=CC2=C1NC=C2C3=NC(=NC=C3)NC4=CN(N=C4OC)C)N5CCN(CC5)C
Molecular Formula
C25H31N9O2
CAS Number
2091134-68-6

Product Categories/Family for AZD 4205 biochemical

Structure of AZD 4205 biochemical

AZD 4205 Biochemical – Cat# MBS3603274

Product References and Citations for AZD 4205 biochemical

1. Jason G. Kettle, et al. AACR Abstract 979: Discovery of the JAK1 selective kinase inhibitor AZD4205.
2. Patent: WO2017050938A120170330, Example 32.

Other Notes

Small volumes of AZD 4205 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD 4205 purchase

MBS3603274 is a biochemical targeting AZD 4205.
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