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Sirt2-PROTAC-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603316

A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sirt2-PROTAC-1, Biochemical
Full Product Name
Sirt2-PROTAC-1
Product Synonym Names
Sirt2-PROTAC-1; Sirt2 PROTAC-1; Sirt2-PROTAC1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
852.942
Suitability
DMSO: >=100mg/mL (117.24mM)
H2O: <0.1mg/mL
Target
PROTAC
Receptor
PROTAC
Chemical Name
2-((4, 6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(4-(2-((2-(2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-1H-1, 2, 3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide
SMILES
O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCCCNC(COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)N=N3)=C2)S1)CSC7=NC(C)=CC(C)=N7
Molecular Formula
C40H40N10O8S2
CAS Number
2098487-75-1

Product Categories/Family for Sirt2-PROTAC-1 biochemical

PROTACs

Structure of Sirt2-PROTAC-1 biochemical

Sirt2-PROTAC-1 Biochemical – Cat# MBS3603316

Product References and Citations for Sirt2-PROTAC-1 biochemical

1. Schiedel M, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01872.

Other Notes

Small volumes of Sirt2-PROTAC-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sirt2-PROTAC-1 purchase

MBS3603316 is a biochemical targeting Sirt2-PROTAC-1.
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