• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LY-411575

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603327

A potent gamma-secretase inhibitor that has an IC50 value of 119 pM for reduction of Abeta levels in APP-transfected cell lines. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY-411575, Biochemical
Full Product Name
LY-411575
Product Synonym Names
LY411575; LY 411575
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
479.4753
Suitability
10mM in DMSO
Target
gamma-secretase
Receptor
NotchS3cleavage; gammasecretase (cell-based); gammasecretase (membrane-based)
Chemical Name
Benzeneacetamide, N-[(1S)-2-[[(7S)-6, 7-dihydro-5-methyl-6-oxo-5H-dibenz[b, d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3, 5-difluoro-.alpha.-hydroxy-, (.alpha.S)
SMILES
C[C@@H](C(N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C)C1=O)=O)NC([C@H](C4=CC(F)=CC(F)=C4)O)=O
Molecular Formula
C26H23F2N3O4
CAS Number
209984-57-6

Product Categories/Family for LY-411575 biochemical

Alzheimer Disease; Wnt/Notch/Hedgehog; Neurological Disease

Structure of LY-411575 biochemical

Ly-411575 Biochemical – Cat# MBS3603327

Product References and Citations for LY-411575 biochemical

1. Lanz TA, et al. J Pharmacol Exp Ther. 2004 Apr; 309 (1):49-55.
2. Best JD, et al. J Pharmacol Exp Ther. 2005 May; 313 (2):902-8.
3. Hyde LA, et al. J Pharmacol Exp Ther. 2006 Dec; 319 (3):1133-43.

Other Notes

Small volumes of LY-411575 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-411575 purchase

MBS3603327 is a biochemical targeting LY-411575.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000