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MCC950

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603349

MCC950 (CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 inflammasome with IC50 of 7.5 and 8.1 nM in BMDM and HMDM, respectively. More details

$215 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCC950, Biochemical
Full Product Name
MCC950
Product Synonym Names
MCC-950; CP-456773
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
404.4799
Suitability
DMSO: >=28mg/mL
Target
NOD
Receptor
NLRP3
Chemical Name
2-Furansulfonamide, N-[[(1, 2, 3, 5, 6, 7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)
SMILES
CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O
Molecular Formula
C20H24N2O5S
CAS Number
210826-40-7

Structure of MCC950 biochemical

MCC950 Biochemical – Cat# MBS3603349

Product References and Citations for MCC950 biochemical

1. Coll RC, et al. Nat Med. 2015 Mar; 21 (3):248-55.
2. Krishnan SM, et al. Br J Pharmacol. 2016 Feb; 173 (4):752-65.
3. Baker PJ, et al. Eur J Immunol. 2015 Oct; 45 (10):2918-26.
4. Primiano MJ, et al. J Immunol. 2016 Sep 15; 197 (6):2421-33.

Other Notes

Small volumes of MCC950 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCC950 purchase

MBS3603349 is a biochemical targeting MCC950.
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