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SNIPER (AR)-51

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603362

SNIPER(AR)-51 is a specific and nongenetic, protein degradation inducer of androgen receptor, consistiong of AR ligand and IAP ligand and linker; induces proteasomal degradation of AR and shows effective protein knockdown activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SNIPER (AR)-51, Biochemical
Full Product Name
SNIPER (AR)-51
Product Synonym Names
SNIPER AR-51
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
984.226
Target
PROTAC
Receptor
PROTAC
Chemical Name
(S)-N-((S)-2-((S)-2-(4-(3-(2-(2-(2-(2-(4-((3-cyano-4-(4-cyanophenyl)-2, 5-dimethyl-1H-pyrrol-1-yl)methyl)phenoxy)ethoxy)ethoxy)ethoxy)ethoxy)benzoyl)thiazol-2-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)-2-(methylamino)propanamide
SMILES
C[C@H](NC)C(N[C@@H](C1CCCCC1)C(N2[C@H](C3=NC(C(C4=CC=CC(OCCOCCOCCOCCOC5=CC=C(CN6C(C)=C(C#N)C(C7=CC=C(C#N)C=C7)=C6C)C=C5)=C4)=O)=CS3)CCC2)=O)=O
Molecular Formula
C55H65N7O8S
CAS Number
2113688-43-8

Product Categories/Family for SNIPER (AR)-51 biochemical

PROTACs; Cancer

Structure of SNIPER (AR)-51 biochemical

SNIPER (AR)-51 Biochemical – Cat# MBS3603362

Product References and Citations for SNIPER (AR)-51 biochemical

1. Shibata N, et al. J Med Chem. 2017 Jun 23. doi: 10.1021/acs.jmedchem.7b00168.

Other Notes

Small volumes of SNIPER (AR)-51 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNIPER (AR)-51 purchase

MBS3603362 is a biochemical targeting SNIPER (AR)-51.
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