Purvalanol A (NG-60)

Name: Purvalanol A (NG-60); MyBioSource
Brand: MyBioSource
SKU: MBS3603387
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603387

A potent, cell-permeable, selective inhibitor of CDK with IC50s of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. More details

$215 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Purvalanol A, Biochemical

Full Product Name

Purvalanol A

Product Synonym Names

NG-60; NG 60; NG60

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

388.8944

Suitability

10mM in DMSO

Target

CDK

Receptor

Cdc2/CyclinB; CDK2/CyclinA; CDK2/CyclinE; CDK4/CyclinD1

Chemical Name

1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)

SMILES

CC(C)[C@@H](NC1=NC(NC2=CC=CC(Cl)=C2)=C3N=CN(C(C)C)C3=N1)CO

Molecular Formula

C19H25ClN6O

CAS Number

212844-53-6

Product Categories/Family for Purvalanol A biochemical

Angiogenesis; Cancer

Product References and Citations for Purvalanol A biochemical

1. Gray NS, et al. Science. 1998 Jul 24; 281 (5376):533-8.
2. Chadebech P, et al. Int J Cancer. 2000 Sep 15; 87 (6):779-86.
3. Obakan P, et al. Mol Biol Rep. 2014 Jan; 41 (1):145-54.

Other Notes

Small volumes of Purvalanol A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Purvalanol A purchase

MBS3603387 is a biochemical targeting Purvalanol A.