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VU661013

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603394

VU661013 (VU-661013) is a novel potent, selective MCL-1 inhibitor with Ki of 97 pM (human MCL-1) in TR-FRET assay. More details

$310 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VU661013, Biochemical
Full Product Name
VU661013
Product Synonym Names
VU 661013; VU-661013
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
712.672
Suitability
DMSO: >=125mg/mL (175.40 m
MH2O: <0.1mg/mL
Target
Bcl-2
Receptor
Bcl-2
Chemical Name
(R)-3-(7-chloro-10-(3-(4-chloro-3, 5-dimethylphenoxy)propyl)-4-methyl-1-oxo-6-(1, 3, 5-trimethyl-1H-pyrazol-4-yl)-3, 4-dihydropyrazino[1, 2-a]indol-2(1H)-yl)-1-methyl-1H-indole-5-carboxylic acid
SMILES
ClC1=C(C2=C(C)N(C)N=C2C)C3=C(C(CCCOC4=CC(C)=C(Cl)C(C)=C4)=C5N3[C@H](C)CN(C6=CN(C)C7=C6C=C(C(O)=O)C=C7)C5=O)C=C1
Molecular Formula
C39H39Cl2N5O4
CAS Number
2131184-57-9

Product Categories/Family for VU661013 biochemical

Structure of VU661013 biochemical

VU661013 Biochemical – Cat# MBS3603394

Product References and Citations for VU661013 biochemical

1. Ramsey HE, et al. Cancer Discov. 2018 Sep 5. pii: CD-18-0140.
2. Zhao B, et al. Biochemistry. 2018 Aug 14; 57 (32):4952-4958.

Other Notes

Small volumes of VU661013 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VU661013 purchase

MBS3603394 is a biochemical targeting VU661013.
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