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dTRIM24

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603466

dTRIM24 is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement). More details

$320 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
dTRIM24, Biochemical
Full Product Name
dTRIM24
Product Synonym Names
dTRIM 24; dTRIM24; dTRIM-24
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1113.312
Suitability
Ethanol: <1mg/mL
Target
PROTAC
Receptor
PROTAC
Chemical Name
(2S, 4R)-1-((S)-15-(tert-butyl)-1-(3-(N-(1, 3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2, 3-dihydro-1 -benzo[ ]imidazol-5-yl)sulfamoyl)phenyl)-1, 13-dioxo-5, 8, 11-trioxa-2, 14-diazahexadecan-16-oyl)-4-hydroxy-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamid
SMILES
O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCNC(C2=CC=CC(S(=O)(NC3=C(OC4=CC=CC(OCCC)=C4)C=C(C(N5C)=C3)N(C)C5=O)=O)=C2)=O)=O)=O)C[C@H](O)C1)NCC6=CC=C(C7=C(C)N=CS7)C=C6
Molecular Formula
C55H68N8O13S2
CAS Number
2170695-14-2

Product Categories/Family for dTRIM24 biochemical

PROTACs

Structure of dTRIM24 biochemical

Dtrim24 Biochemical – Cat# MBS3603466

Product References and Citations for dTRIM24 biochemical

1. Gechijian LN, et al. Nat Chem Biol. 2018 Mar 5. doi: 10.1038/s41589-018-0010-y.

Other Notes

Small volumes of dTRIM24 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for dTRIM24 purchase

MBS3603466 is a biochemical targeting dTRIM24.
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