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PD173074

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603497

PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PD173074, Biochemical
Full Product Name
PD173074
Product Synonym Names
PD173074; PD 173074; PD-173074
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
523.67
Suitability
Ethanol: 100mg/mL (190.95mM)
DMSO: 100mg/mL (190.95mM)
Target
EGFR
Receptor
EGFR; FGFR1; Insulin Receptor; c-Src; VEGFR2
Chemical Name
1-(tert-butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3, 5-dimethoxyphenyl)pyrido[2, 3-d]pyrimidin-7-yl)urea
SMILES
O=C(NC1=NC2=NC(NCCCCN(CC)CC)=NC=C2C=C1C3=CC(OC)=CC(OC)=C3)NC(C)(C)C
Molecular Formula
C28H41N7O3
CAS Number
219580-11-7

Product Categories/Family for PD173074 biochemical

Structure of PD173074 biochemical

PD173074 Biochemical – Cat# MBS3603497

Product References and Citations for PD173074 biochemical

1.Mohammadi M, et al. EMBO J, 1998, 17 (20), 5896-5904.

Other Notes

Small volumes of PD173074 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PD173074 purchase

MBS3603497 is a biochemical targeting PD173074.
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