Zotarolimus (ABT-578)

Name: Zotarolimus (ABT-578); MyBioSource
Brand: MyBioSource
SKU: MBS3603535
Price: 255 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603535

Zotarolimus (ABT-578, A 179578) is a semi-synthetic analogue of rapamycin, inhibits FKBP-12. More details

$255 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Zotarolimus, Biochemical

Full Product Name

Zotarolimus

Product Synonym Names

ABT-578; A-179578; ABT578; A179578; ABT 578; A 179578

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

966.21

Suitability

DMSO: >=33mg/mL

Target

mTOR

Receptor

FKBP-12

Chemical Name

Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)

SMILES

O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)CC[C@@](O2)([H])C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@H]3C)=O)=O)=O)O[C@H]([C@H](C)C[C@H]4C[C@@H](OC)[C@@H](N5N=NN=C5)CC4)CC3=O

Molecular Formula

C52H79N5O12

CAS Number

221877-54-9

Product Categories/Family for Zotarolimus biochemical

PI3K/Akt/mTOR signaling; Cancer

Product References and Citations for Zotarolimus biochemical

1. Garcia-Touchard A, et al. Eur Heart J. 2006 Apr; 27 (8):988-93.
2. Chen YW, et al. J Cardiovasc Pharmacol. 2007 Apr; 49 (4):228-35.
3. Abizaid A, et al. Am J Cardiol. 2007 May 15; 99 (10):1403-8.
4. Wagner R, et al. Bioorg Med Chem Lett. 2005 Dec 1; 15 (23):5340-3.

Other Notes

Small volumes of Zotarolimus biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Zotarolimus purchase

MBS3603535 is a biochemical targeting Zotarolimus.