MS4078

Name: MS4078; MyBioSource
Brand: MyBioSource
SKU: MBS3603563
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603563

MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM). More details

$250 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MS4078, Biochemical

Full Product Name

MS4078

Product Synonym Names

MS-4078; MS 4078

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

914.476

Target

PROTAC

Receptor

PROTAC

Chemical Name

2-(4-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-((2-(2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-4-yl)amino)ethyl)acetamide

SMILES

O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN4CCC(C5=CC(OC(C)C)=C(NC6=NC=C(Cl)C(NC7=CC=CC=C7S(=O)(C(C)C)=O)=N6)C=C5C)CC4

Molecular Formula

C45H52ClN9O8S

CAS Number

2229036-62-6

Product Categories/Family for MS4078 biochemical

PROTACs

Product References and Citations for MS4078 biochemical

1. Zhang C, et al. Eur J Med Chem. 2018 May 10; 151:304-314.

Other Notes

Small volumes of MS4078 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MS4078 purchase

MBS3603563 is a biochemical targeting MS4078.

MS4078

Product Overview

Product Categories/Family for MS4078 biochemical

Structure of MS4078 biochemical

Related Product Information for MS4078 biochemical

Product References and Citations for MS4078 biochemical

Other Notes

Searchable Terms for MS4078 purchase