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Fg-2216 (YM-311)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603579

FG-2216 (YM-311, IOX3) is a selective small molecule inhibitor of HIF prolyl hydroxylase with IC50 of 3.9 nM (PDH2). More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FG-2216, Biochemical
Full Product Name
FG-2216
Product Synonym Names
YM-311; IOX3
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
280.7
Suitability
DMSO: >=31mg/mL
Target
HIF/HIF Prolyl-hydroxylase
Receptor
PHD2
Chemical Name
Glycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]
SMILES
OC1=C(C(NCC(O)=O)=O)N=C(Cl)C2=CC=CC=C21
Molecular Formula
C12H9ClN2O4
CAS Number
223387-75-5

Product Categories/Family for FG-2216 biochemical

Structure of FG-2216 biochemical

Fg-2216 YM-311 Biochemical – Cat# MBS3603579

Product References and Citations for FG-2216 biochemical

1. Hong YR, et al. Bioorg Med Chem Lett. 2013 Nov 1; 23 (21):5953-7.
2. McMurray F, et al. PLoS One. 2015 Apr 1; 10 (4):e0121829.
3. Hsieh MM, et al. Blood. 2007 Sep 15; 110 (6):2140-7.
4. Aik W, et al. Nucleic Acids Res. 2014 Apr; 42 (7):4741-54.

Other Notes

Small volumes of FG-2216 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FG-2216 purchase

MBS3603579 is a biochemical targeting FG-2216.
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