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MK-0429

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603623

MK-0429 is a potent, selective, orally-active nonpeptide alphavbeta3 integrin inhibitor with IC50 of 0.08 nM in SPAV3 assay. More details

$1525 / 50 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-0429, Biochemical
Full Product Name
MK-0429
Product Synonym Names
MK0429
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
439.51
Suitability
DMSO: 250mg/mL (568.82mM)
Target
Integrin
Receptor
Integrin
Chemical Name
(S)-3-(6-methoxypyridin-3-yl)-3-(2-oxo-3-(3-(5, 6, 7, 8-tetrahydro-1, 8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoic acid
SMILES
O=C(O)C[C@@H](C1=CC=C(OC)N=C1)N2CCN(CCCC3=NC4=C(CCCN4)C=C3)C2=O
Molecular Formula
C23H29N5O4
CAS Number
227963-15-7

Product Categories/Family for MK-0429 biochemical

Prostate Cancer; Cell Cycle/DNA Damage; Cancer

Structure of MK-0429 biochemical

Mk-0429 Biochemical – Cat# MBS3603623

Product References and Citations for MK-0429 biochemical

1. Hutchinson JH, et al. J Med Chem. 2003 Oct 23; 46 (22):4790-8.
2. Pickarski M, et al. Oncol Rep. 2015 Jun; 33 (6):2737-45.
3. Zhou X, et al. Pharmacol Res Perspect. 2017 Oct; 5 (5).

Other Notes

Small volumes of MK-0429 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0429 purchase

MBS3603623 is a biochemical targeting MK-0429.
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