Lapatinib (GW572016)

Name: Lapatinib (GW572016); MyBioSource
Brand: MyBioSource
SKU: MBS3603649
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603649

A reversible, selective dual tyrosine kinase inhibitor of both EGFR and ErbB2 with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. More details

$215 / 10 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lapatinib, Biochemical

Full Product Name

Lapatinib

Product Synonym Names

GW572016; GW-572016; GW 572016

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

581.0576

Suitability

DMSO: >=39mg/mL

Target

EGFR

Receptor

C-Raf-1; c-Src; EGFR; HER2/ErbB2

Chemical Name

4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]

SMILES

CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(C=C1)N=CN=C2NC1=CC(Cl)=C(OCC2=CC(F)=CC=C2)C=C1

Molecular Formula

C29H26ClFN4O4S

CAS Number

231277-92-2

Product Categories/Family for Lapatinib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Lapatinib biochemical

1. Xia W, et al. Oncogene. 2002 Sep 12; 21 (41):6255-63.
2. Rusnak DW, et al. Mol Cancer Ther. 2001 Dec; 1 (2):85-94.
3. Konecny GE, et al. Cancer Res. 2006 Feb 1; 66 (3):1630-9.

Other Notes

Small volumes of Lapatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lapatinib purchase

MBS3603649 is a biochemical targeting Lapatinib.