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ALE-0540

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603670

ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALE-0540, Biochemical
Full Product Name
ALE-0540
Product Synonym Names
ALE0540
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
301.258
Target
Trk Receptor
Receptor
Trk Receptor
Chemical Name
2-(2-Hydroxyethylamino)-5-nitrobenzo[de]isoquinoline-1, 3-dione
SMILES
c1cc2cc(cc3c2c(c1)C(=O)N(C3=O)NCCO)[N+](=O)[O-]
Molecular Formula
C14H11N3O5
CAS Number
234779-34-1

Product Categories/Family for ALE-0540 biochemical

Pain; Tyrosine Kinase; Neurological Disease

Structure of ALE-0540 biochemical

ALE-0540 Biochemical – Cat# MBS3603670

Product References and Citations for ALE-0540 biochemical

1. Owolabi JB, et al. J Pharmacol Exp Ther. 1999 Jun; 289 (3):1271-6.
2. Eibl JK, et al. Eur J Pharmacol. 2013 May 15; 708 (1-3):30-7.
3. Sheffield KS, et al. Pharmacol Res. 2016 Jan; 103:292-9.

Other Notes

Small volumes of ALE-0540 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALE-0540 purchase

MBS3603670 is a biochemical targeting ALE-0540.
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