TPA023 (MK-0777)

Name: TPA023 (MK-0777); MyBioSource
Brand: MyBioSource
SKU: MBS3603748
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603748

TPA023 is a potent, alpha2/alpha3 subtype-selective, and oral GABAA receptor agonist with Kd of 0.92, 1.05 and 0.58 nM for alpha1-, alpha2-, alpha3-, and alpha5-containing human receptors. More details

$295 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TPA023, Biochemical

Full Product Name

TPA023

Product Synonym Names

MK-0777

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

395.442

Target

GAT

Receptor

GAT

Chemical Name

7-(1, 1-Dimethylethyl)-6-(2-ethyl-2H-1, 2, 4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1, 2, 4-triazolo[4, 3-b]pyridazine

SMILES

FC1=CC=CC=C1C2=NN=C3C=C(C(C)(C)C)C(OCC4=NC=NN4CC)=NN32

Molecular Formula

C20H22FN7O

CAS Number

252977-51-8

Product Categories/Family for TPA023 biochemical

Anxiety; Membrane Transporter/Ion Channel; Neurological Disease

Product References and Citations for TPA023 biochemical

1. Atack JR, et al. J Pharmacol Exp Ther. 2010 Jan; 332 (1):17-25.
2. de Haas SL, et al. J Psychopharmacol. 2007 Jun; 21 (4):374-83.
3. Carling RW, et al. J Med Chem. 2005 Nov 17; 48 (23):7089-92.
4. Atack JR, et al. J Pharmacol Exp Ther. 2006 Jan; 316 (1):410-22.

Other Notes

Small volumes of TPA023 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TPA023 purchase

MBS3603748 is a biochemical targeting TPA023.