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5Z-7-Oxozeaenol

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603757

A potent, selective TAK1 inhibitor with IC50 of 8 nM, displays >33-fold and >62-fold selectivity over MEKK1 and MEKK4 respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
5Z-7-Oxozeaenol, Biochemical
Full Product Name
5Z-7-Oxozeaenol
Product Synonym Names
5Z)-7-Oxozeaenol; TAK1 inhibitor 5ZO
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
362.37
Suitability
DMSO: 50mg/mL (137.98mM)
Target
TAK1
Receptor
TAK1
Chemical Name
(3S, 5Z, 8S, 9S, 11E)-3, 4, 9, 10-tetrahydro-8, 9, 16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1, 7(8H)-dione
SMILES
O=C(O[C@@H](C)C/C=C1)C2=C(O)C=C(OC)C=C2/C=C/C[C@H](O)[C@H](O)C1=O
Molecular Formula
C19H22O7
CAS Number
253863-19-3

Product Categories/Family for 5Z-7-Oxozeaenol biochemical

NF-kappaB

Structure of 5Z-7-Oxozeaenol biochemical

5z-7-Oxozeaenol Biochemical – Cat# MBS3603757

Product References and Citations for 5Z-7-Oxozeaenol biochemical

1. Ninomiya-Tsuji J, et al. J Biol Chem. 2003 May 16; 278 (20):18485-90.
2. Choo MK, et al. Mol Cancer Ther. 2006 Dec; 5 (12):2970-6.
3. Sogabe Y, et al. Bioorg Med Chem Lett. 2015 Feb 1; 25 (3):593-6.
4. Fan Y, et al. Apoptosis. 2013 Oct; 18 (10):1224-34.

Other Notes

Small volumes of 5Z-7-Oxozeaenol biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 5Z-7-Oxozeaenol purchase

MBS3603757 is a biochemical targeting 5Z-7-Oxozeaenol.
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