• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NPS-2143

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603863

MBS3603863 is a biochemical targeting NPS-2143. A potent, selective and orally active CaSR antagonist with IC50 of 43 nM. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NPS-2143, Biochemical
Full Product Name
NPS-2143
Product Synonym Names
NPS 2143; SB-262470; NPS2143; SB 262470
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
408.9205
Suitability
10mM in DMSO
Target
CaSR
Receptor
Ca (2+)receptor
Chemical Name
Benzonitrile, 2-chloro-6-[(2R)-3-[[1, 1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]
SMILES
CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
Molecular Formula
C24H25ClN2O2
CAS Number
284035-33-2

Product Categories/Family for NPS-2143 biochemical

Osteoporosis; GPCR/G Protein; Metabolic Disease

Structure of NPS-2143 biochemical

NPS-2143 Biochemical – Cat# MBS3603863

Product References and Citations for NPS-2143 biochemical

1. Gowen M, et al. J Clin Invest. 2000 Jun; 105 (11):1595-604.
2. Nemeth EF, et al. J Pharmacol Exp Ther. 2001 Oct; 299 (1):323-31.
3. Lee JW, et al. Mol Immunol. 2017 Oct; 90:150-157.

Other Notes

Small volumes of NPS-2143 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000