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Cediranib (AZD2171)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603882

A highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cediranib, Biochemical
Full Product Name
Cediranib
Product Synonym Names
AZD2171; AZD 2171; AZD-2171
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
450.5053
Suitability
DMSO: >=49mg/mL
Target
VEGFR
Receptor
c-Kit; PDGFRbeta; VEGFR1/FLT1; VEGFR2/KDR; VEGFR3/FLT4
Chemical Name
Quinazoline, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]
SMILES
COC1=C(OCCCN2CCCC2)C=C2N=CN=C(OC3=C(F)C4=C(NC(C)=C4)C=C3)C2=C1
Molecular Formula
C25H27FN4O3
CAS Number
288383-20-0

Product References and Citations for Cediranib biochemical

1. Wedge SR, et al. Cancer Res. 2005 May 15; 65 (10):4389-400.
2. Denduluri N, et al. Clin Breast Cancer. 2005 Dec; 6 (5):460-3.
3. Batchelor TT, et al. Cancer Cell. 2007 Jan; 11 (1):83-95.
4. Cao C, et al. Cancer Res. 2006 Dec 1; 66 (23):11409-15.

Other Notes

Small volumes of Cediranib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cediranib purchase

MBS3603882 is a biochemical targeting Cediranib.
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