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D4476

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603943

D4476 (Casein Kinase I Inhibitor, D 4476, D-4476) is a potent, selective ATP-competitive inhibitor of CK1 with IC50 of 0.3 uM in vitro. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
D4476, Biochemical
Full Product Name
D4476
Product Synonym Names
Casein Kinase I Inhibitor; D 4476; D-4476
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
398.414
Suitability
10mM in DMSO
Target
Casein Kinase
Receptor
ALK5; CK1; CK1delta
Chemical Name
Benzamide, 4-[4-(2, 3-dihydro-1, 4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]
SMILES
O=C(N)C1=CC=C(C2=NC(C3=CC=C(OCCO4)C4=C3)=C(C5=NC=CC=C5)N2)C=C1
Molecular Formula
C23H18N4O3
CAS Number
301836-43-1

Product Categories/Family for D4476 biochemical

Product References and Citations for D4476 biochemical

1. Rena G, et al. EMBO Rep. 2004 Jan; 5 (1):60-5.
2. Bryja V, et al. Cell Signal. 2007 Mar; 19 (3):610-6.
3. Huart AS, et al. J Biol Chem. 2009 Nov 20; 284 (47):32384-94.

Other Notes

Small volumes of D4476 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for D4476 purchase

MBS3603943 is a biochemical targeting D4476.
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