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SB-435495

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603963

MBS3603963 is a biochemical targeting SB-435495. SB-435495 is a potent, orally active inhibitor of Lp-PLA2 with IC50 of 0.06 nM. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-435495, Biochemical
Full Product Name
SB-435495
Product Synonym Names
SB435495
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
720.832
Target
Phospholipase
Receptor
Phospholipase
Chemical Name
1(4H)-Pyrimidineacetamide, N-[2-(diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-5-[(1-methyl-1H-pyrazol-4-yl)methyl]-4-oxo-N-[[4'-(trifluoromethyl)[1, 1'-biphenyl]-4-yl]methyl]
SMILES
CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C=C(C(=O)N=C3SCC4=CC=C(C=C4)F)CC5=CN(N=C5)C
Molecular Formula
C38H40F4N6O2S
CAS Number
304694-39-1

Product Categories/Family for SB-435495 biochemical

Atherosclerosis; Metabolic Enzyme/Protease; Cardiovascular Disease

Structure of SB-435495 biochemical

Sb-435495 Biochemical – Cat# MBS3603963

Product References and Citations for SB-435495 biochemical

1. Blackie JA, et al. Bioorg Med Chem Lett. 2002 Sep 16; 12 (18):2603-6.
2. Canning P, et al. Proc Natl Acad Sci U S A. 2016 Jun 28; 113 (26):7213-8.
3. Tyurin VA, et al. Cell Death Differ. 2014 May; 21 (5):825-35.
4. Jiang Z, et al. Respir Res. 2012 Nov 12; 13:100.

Other Notes

Small volumes of SB-435495 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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