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SMER-28

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603982

A small-molecule enhancer/inducer of Autophagy; decreases the levels of Abeta peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a gamma-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the… More details

$215 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMER-28, Biochemical
Full Product Name
SMER-28
Product Synonym Names
SMER28
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
264.1212
Suitability
DMSO: >=32mg/mL
Target
Autophagy
Receptor
Autophagy
Chemical Name
4-Quinazolinamine, 6-bromo-N-2-propen-1-yl
SMILES
C=CCNC1=C2C=C(Br)C=CC2=NC=N1
Molecular Formula
C11H10BrN3
CAS Number
307538-42-7

Product Categories/Family for SMER-28 biochemical

Autophagy; Neurological Disease

Structure of SMER-28 biochemical

SMER-28 Biochemical – Cat# MBS3603982

Product References and Citations for SMER-28 biochemical

1. Doulatov S, et al. Sci Transl Med. 2017 Feb 8; 9 (376). pii: eaah5645.
2. Rosenthal AK, et al. J Biol Chem. 2015 May 22; 290 (21):13028-38.
3. Sarkar S, et al. Nat Chem Biol. 2007 Jun; 3 (6):331-8.
4. Tian Y et al. FASEB J. 2011 Jun; 25 (6):1934-42.

Other Notes

Small volumes of SMER-28 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMER-28 purchase

MBS3603982 is a biochemical targeting SMER-28.
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